Shay chloroma alkaline phosphatase

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منابع مشابه

Purification and properties of alkaline phosphatase from rat chloroma.

Activity was determined by the rate of hydrolysis of 13-glycerophosphate on p-nitrophenyl phosphate (8). The determination with sodium 13-glycerophosphate was carried out as follows. The reaction mixture consisted of 0.05 M Tnis-HC1 (pH 10), 0.023 M sodium 13-glycerophosphate, 0.004 M MgCl2, and enzyme in a final volume of 2 ml. After incubation at 37° for 30 mm, 2 ml of 10% tnicbloroacetic ac...

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Porphyrin concentration and myeloperoxydase activity in the tissues of the Shay chloroma of the rat.

BSERVATIONS on human chloroleukemic tissue have shown that it contains porphyrin, which accounts for its red fluorescence in Wood’s light1 and an enzyme, myeloperoxydase (or verdoperoxydase), to which the green color of the chloroleukemic tissue is due.2 In recent years many chloroleukemic tumors have been described in animals where the tumor tissue also contained porphyrin and myeloperoxydase....

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Fluoride and Alkaline Phosphatase

Since serum alkaline phosphatase increases in fluoride therapy for osteoporosis, it is generally accepted that fluoride stimulates bone formation. However, histochemical studies have shown that alkaline phosphatase is also increased in resorbing osteocytes. Fluoride is toxic to metabolically active bone cells, alkaline phosphatase is released, and serum alkaline phosphatase increases. We propos...

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Chicken Intestinal Alkaline Phosphatase

Purified chicken intestinal alkaline phosphatase is active at pH 8 to 9, but becomes rapidly inactivated with change of pH to 6 or less. Also, a solution of the inactivated enzyme at pH 4.5 rapidly regains its activity at pH 8. In the range of pH 6 to 8 a solution of purified alkaline phosphatase consists of a mixture of active and inactive enzyme in equilibrium with each other. The rate of ina...

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Alkaline Phosphatase of Milk

inor i8obutanol. Removal of the lipid is accompanied by simultaneous release of the enzyme into true solution. No other organic solvent tested was effective in releasing the bound phosphatase, indicating a unique action of butanol. I wish to thank Dr M. Dixon, F.R.S., for his encouraging interest and advice during this work. This work was carried out while holding a Travelling Scholarship award...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1968

ISSN: 0264-6021,1470-8728

DOI: 10.1042/bj1100012pa